The genomic origins of asthma.
Ontology highlight
ABSTRACT:
SUBMITTER: Sharma S
PROVIDER: S-EPMC4343201 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Publications
The genomic origins of asthma.
Sharma Sunita S Chhabra Divya D Kho Alvin T AT Hayden Lystra P LP Tantisira Kelan G KG Weiss Scott T ST
Thorax 20140325 5
Lung function tracks from the earliest age that it can be reliably measured. Genome wide association studies suggest that most variants identified for common complex traits are regulatory in function and active during fetal development. Fetal programming of gene expression during development is critical to the formation of a normal lung. An understanding of how fetal developmental genes related to diseases of the lungs and airways is a critical area for research. This review article considers th ...[more]
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