Dataset Information

Survival nomogram for curatively resected Korean gastric cancer patients: multicenter retrospective analysis with external validation.

ABSTRACT:

Background

A small number of nomograms have been previously developed to predict the individual survival of patients who undergo curative resection for gastric cancer. However, all were derived from single high-volume centers. The aim of this study was to develop and validate a nomogram for gastric cancer patients using a multicenter database.

Methods

We reviewed the clinicopathological and survival data of 2012 patients who underwent curative resection for gastric cancer between 2001 and 2006 at eight centers. Among these centers, six institutions were randomly assigned to the development set, and the other two centers were assigned to the validation set. Multivariate analysis using the Cox proportional hazard regression model was performed, and discrimination and calibration were evaluated by external validation.

Results

Multivariate analyses revealed that age, tumor size, lymphovascular invasion, depth of invasion, and metastatic lymph nodes were significant prognostic factors for overall survival. In the external validation, the concordance index was 0.831 (95% confidence interval, 0.784-0.878), and Hosmer-Lemeshow chi-square statistic was 3.92 (P = 0.917).

Conclusions

We developed and validated a nomogram to predict 5-year overall survival after curative resection for gastric cancer based on a multicenter database. This nomogram can be broadly applied even in general hospitals and is useful for counseling patients, and scheduling follow-up.

SUBMITTER: Eom BW

PROVIDER: S-EPMC4344235 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Publications

Survival nomogram for curatively resected Korean gastric cancer patients: multicenter retrospective analysis with external validation.

Eom Bang Wool BW Ryu Keun Won KW Nam Byung-Ho BH Park Yunjin Y Lee Hyuk-Joon HJ Kim Min Chan MC Cho Gyu Seok GS Kim Chan Young CY Ryu Seung Wan SW Shin Dong Woo DW Hyung Woo Jin WJ Lee Jun Ho JH

PloS one 20150227 2

<h4>Background</h4>A small number of nomograms have been previously developed to predict the individual survival of patients who undergo curative resection for gastric cancer. However, all were derived from single high-volume centers. The aim of this study was to develop and validate a nomogram for gastric cancer patients using a multicenter database.<h4>Methods</h4>We reviewed the clinicopathological and survival data of 2012 patients who underwent curative resection for gastric cancer between ...[more]

PMID: 25723182

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Dataset Information

Survival nomogram for curatively resected Korean gastric cancer patients: multicenter retrospective analysis with external validation.

Background

Methods

Results

Conclusions

Publications

Survival nomogram for curatively resected Korean gastric cancer patients: multicenter retrospective analysis with external validation.

Similar Datasets

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