Ontology highlight
ABSTRACT:
SUBMITTER: Riabinina O
PROVIDER: S-EPMC4344399 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Riabinina Olena O Luginbuhl David D Marr Elizabeth E Liu Sha S Wu Mark N MN Luo Liqun L Potter Christopher J CJ
Nature methods 20150112 3
The Q system is a repressible binary expression system for transgenic manipulations in living organisms. Through protein engineering and in vivo functional tests, we report here variants of the Q-system transcriptional activator, including QF2, for driving strong and ubiquitous expression in all Drosophila tissues. Our QF2, Gal4QF and LexAQF chimeric transcriptional activators substantially enrich the toolkit available for transgenic regulation in Drosophila melanogaster. ...[more]