Ontology highlight
ABSTRACT:
SUBMITTER: Linford NJ
PROVIDER: S-EPMC4345594 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Linford Nancy J NJ Ro Jennifer J Chung Brian Y BY Pletcher Scott D SD
Proceedings of the National Academy of Sciences of the United States of America 20150209 8
Sleep loss is an adaptive response to nutrient deprivation that alters behavior to maximize the chances of feeding before imminent death. Organisms must maintain systems for detecting the quality of the food source to resume healthy levels of sleep when the stress is alleviated. We determined that gustatory perception of sweetness is both necessary and sufficient to suppress starvation-induced sleep loss when animals encounter nutrient-poor food sources. We further find that blocking specific do ...[more]