Ontology highlight
ABSTRACT:
SUBMITTER: Rimal S
PROVIDER: S-EPMC6490183 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Cell reports 20190201 6
The decision to consume or reject a food based on the degree of acidity is critical for animal survival. However, the gustatory receptors that detect sour compounds and influence feeding behavior have been elusive. Here, using the fly, Drosophila melanogaster, we reveal that a member of the ionotropic receptor family, IR7a, is essential for rejecting foods laced with high levels of acetic acid. IR7a is dispensable for repulsion of other acidic compounds, indicating that the gustatory sensation o ...[more]