Ontology highlight
ABSTRACT:
SUBMITTER: Laronda MM
PROVIDER: S-EPMC4350019 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Laronda Monica M MM Jakus Adam E AE Whelan Kelly A KA Wertheim Jason A JA Shah Ramille N RN Woodruff Teresa K TK
Biomaterials 20150214
Clinical interventions to preserve fertility and restore hormone levels in female patients with therapy-induced ovarian failure are insufficient, particularly for pediatric cancer patients. Laparoscopic isolation of cortical ovarian tissue followed by cryopreservation with subsequent autotransplantation has temporarily restored fertility in at least 27 women who survived cancer, and aided in pubertal transition for one pediatric patient. However, reintroducing cancer cells through ovarian transp ...[more]