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ABSTRACT:
SUBMITTER: Chojnowski G
PROVIDER: S-EPMC4356372 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Chojnowski Grzegorz G Waleń Tomasz T Piątkowski Paweł P Potrzebowski Wojciech W Bujnicki Janusz M JM
Acta crystallographica. Section D, Biological crystallography 20150226 Pt 3
Brickworx is a computer program that builds crystal structure models of nucleic acid molecules using recurrent motifs including double-stranded helices. In a first step, the program searches for electron-density peaks that may correspond to phosphate groups; it may also take into account phosphate-group positions provided by the user. Subsequently, comparing the three-dimensional patterns of the P atoms with a database of nucleic acid fragments, it finds the matching positions of the double-stra ...[more]