Ontology highlight
ABSTRACT:
SUBMITTER: Gupta R
PROVIDER: S-EPMC4357020 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Gupta Rishein R Arkatkar Tanvi T Yu Jieh-Juen JJ Wali Shradha S Haskins William E WE Chambers James P JP Murthy Ashlesh K AK Bakar Sazaly Abu SA Guentzel M Neal MN Arulanandam Bernard P BP
American journal of reproductive immunology (New York, N.Y. : 1989) 20140628 2
<h4>Problem</h4>Chlamydia trachomatis (CT) is the leading sexually transmitted bacterial infection in humans and is associated with reproductive tract damage. However, little is known about the involvement and regulation of microRNAs (miRs) in genital CT.<h4>Methods</h4>We analyzed miRs in the genital tract (GT) following C. muridarum (murine strain of CT) challenge of wild type (WT) and CD4(+) T-cell deficient (CD4(-/-)) C57BL/6 mice at days 6 and 12 post-challenge.<h4>Results</h4>At day 6, miR ...[more]