Ontology highlight
ABSTRACT:
SUBMITTER: Maes E
PROVIDER: S-EPMC4361338 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Maes Evelyne E Valkenborg Dirk D Baggerman Geert G Willems Hanny H Landuyt Bart B Schoofs Liliane L Mertens Inge I
PloS one 20150316 3
In quantitative shotgun proteomic analyses by liquid chromatography and mass spectrometry, a rigid study design is necessary in order to obtain statistically relevant results. Hypothesis testing, sample size calculation and power estimation are fundamental concepts that require consideration upon designing an experiment. For this reason, the reproducibility and variability of the proteomic platform needs to be assessed. In this study, we evaluate the technical (sample preparation), labeling (iso ...[more]