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3?,5?-Cyclocholestan-6?-yl ethers as donors of the cholesterol moiety for the electrochemical synthesis of cholesterol glycoconjugates.

ABSTRACT: 3?,5?-Cyclocholestan-6?-yl alkyl and aryl ethers were proved to be efficient cholesteryl donors in the electrochemical synthesis of glycoconjugates. 3?,5?-Cyclocholestan-6?-ol (i-cholesterol) and its tert-butyldimethylsilyl ether can also be used for this purpose. The i-cholesterol derivatives show similar reactivities to those of previously studied 3?,5?-cyclocholestan-6?-thioethers.

SUBMITTER: Tomkiel AM

PROVIDER: S-EPMC4362039 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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3α,5α-Cyclocholestan-6β-yl ethers as donors of the cholesterol moiety for the electrochemical synthesis of cholesterol glycoconjugates.

Tomkiel Aneta M AM Biedrzycki Adam A Płoszyńska Jolanta J Naróg Dorota D Sobkowiak Andrzej A Morzycki Jacek W JW

Beilstein journal of organic chemistry 20150126

3α,5α-Cyclocholestan-6β-yl alkyl and aryl ethers were proved to be efficient cholesteryl donors in the electrochemical synthesis of glycoconjugates. 3α,5α-Cyclocholestan-6β-ol (i-cholesterol) and its tert-butyldimethylsilyl ether can also be used for this purpose. The i-cholesterol derivatives show similar reactivities to those of previously studied 3α,5α-cyclocholestan-6β-thioethers. ...[more]

PMID: 25815065

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