Ontology highlight
ABSTRACT:
SUBMITTER: Nitta KR
PROVIDER: S-EPMC4362205 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Nitta Kazuhiro R KR Jolma Arttu A Yin Yimeng Y Morgunova Ekaterina E Kivioja Teemu T Akhtar Junaid J Hens Korneel K Toivonen Jarkko J Deplancke Bart B Furlong Eileen E M EE Taipale Jussi J
eLife 20150317
Divergent morphology of species has largely been ascribed to genetic differences in the tissue-specific expression of proteins, which could be achieved by divergence in cis-regulatory elements or by altering the binding specificity of transcription factors (TFs). The relative importance of the latter has been difficult to assess, as previous systematic analyses of TF binding specificity have been performed using different methods in different species. To address this, we determined the binding s ...[more]