Ontology highlight
ABSTRACT:
SUBMITTER: Broichhausen C
PROVIDER: S-EPMC4362366 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Broichhausen Christiane C Riquelme Paloma P Ahrens Norbert N Wege Anja K AK Koehl Gudrun E GE Schlitt Hans J HJ Banas Bernhard B Fändrich Fred F Geissler Edward K EK Hutchinson James A JA
Molecular therapy. Methods & clinical development 20140716
A new cell-based medicinal product containing human regulatory macrophages, known as Mreg_UKR, has been developed and conforms to expectations of a therapeutic drug. Here, Mreg_UKR was subjected to pharmacokinetic, safety pharmacology, and toxicological testing, which identified no adverse reactions. These results would normally be interpreted as evidence of the probable clinical safety of Mreg_UKR; however, we contend that, owing to their uncertain biological relevance, our data do not fully su ...[more]