Ontology highlight
ABSTRACT:
SUBMITTER: Briggs K
PROVIDER: S-EPMC5598263 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Briggs Katharine K Barber Chris C Cases Montserrat M Marc Philippe P Steger-Hartmann Thomas T
Toxicology reports 20141218
A first analysis of a database of shared preclinical safety data for 1214 small molecule drugs and drug candidates extracted from 3970 reports donated by thirteen pharmaceutical companies for the eTOX project (www.etoxproject.eu) is presented. Species, duration of exposure and administration route data were analysed to assess if large enough subsets of homogenous data are available for building <i>in silico</i> predictive models. Prevalence of treatment related effects for the different types of ...[more]