Ontology highlight
ABSTRACT:
SUBMITTER: Lee Y
PROVIDER: S-EPMC4369324 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Lee Y Y Zacharias N M NM Piwnica-Worms D D Bhattacharya P K PK
Chemical communications (Cambridge, England) 20141101 86
Here we present a novel hyperpolarization method, Chemical Reaction-Induced Multi-molecular Polarization (CRIMP), which could be applied to the study of several in vivo processes simultaneously including glycolysis, TCA cycle, fatty acid synthesis and pH mapping. Through the use of non-enzymatic decarboxylation, we generate four hyperpolarized imaging agents from hyperpolarized 1,2-(13)C pyruvic acid. ...[more]