Effects of age, sex, and menopausal status on blood cholesterol profile in the korean population.

ABSTRACT: BACKGROUND AND OBJECTIVES:To investigate age-specific and sex-specific distributions of blood cholesterol in the general Korean population. SUBJECTS AND METHODS:We analyzed data for 8284 men and 9246 women aged ?10 years who participated in the fifth (2010-2012) Korea National Health and Nutrition Examination Survey. Age-specific means, medians, and selected percentiles were calculated for men, premenopausal women, and postmenopausal women. RESULTS:Median total cholesterol (TC) level increased with age across all age groups, from 147 to 196 mg/dL in males and from 159 to 210 mg/dL in females. Triglyceride (TG) levels increased with age in females; however, in males, TG levels rapidly increased during young adulthood, peaked at 50-54 years, and then decreased. High density lipoprotein-cholesterol (HDL-C) levels were higher in females than in males and decreased with increasing age in both males and females. Low density lipoprotein-cholesterol (LDL-C) levels increased with age across all age groups, from 89 to 127 mg/dL in males and from 82 to 113 mg/dL in females. Lipoprotein-cholesterol fraction (TC/HDL-C, LDL-C/HDL-C, TG/HDL-C, non-HDL-C) levels increased with age in females, but increased more rapidly in males during young adulthood and decreased after middle age. CONCLUSION:Blood cholesterol levels and lipoprotein-cholesterol fractions present different distributions by age, sex, and menopausal status.

SUBMITTER: Park JH 

PROVIDER: S-EPMC4372980 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature