Sarcopenia-related parameters and incident disability in older persons: results from the "invecchiare in Chianti" study.

ABSTRACT:

Background

Current operational definitions of sarcopenia are based on algorithms' simultaneous considering measures of skeletal muscle mass and muscle-specific as well as global function. We hypothesize that quantitative and qualitative sarcopenia-related parameters may not be equally predictive of incident disability, thus presenting different clinical relevance.

Methods

Data are from 922 elder adults (mean age = 73.9 years) with no activities of daily living (ADL) impairment recruited in the "Invecchiare in Chianti" study. Incident disability in ≥1 ADL defined the outcome of interest. The specific capacities of following sarcopenia-related parameters at predicting incident ADL disability were compared: residuals of skeletal muscle mass, fat-adjusted residuals of skeletal m

SUBMITTER: Cesari M 

PROVIDER: S-EPMC4375415 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature