Ontology highlight
ABSTRACT:
SUBMITTER: Desurmont T
PROVIDER: S-EPMC4376434 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Desurmont Thibault T Skrypek Nicolas N Duhamel Alain A Jonckheere Nicolas N Millet Guillaume G Leteurtre Emmanuelle E Gosset Pierre P Duchene Belinda B Ramdane Nassima N Hebbar Mohamed M Van Seuningen Isabelle I Pruvot François-René FR Huet Guillemette G Truant Stéphanie S
Cancer science 20150305 3
Our aim was to analyze the potential role of chemokine receptors CXCR2 and CXCR4 signalling pathways in liver metastatic colorectal cancer (CRC) relapse. CXCR2, CXCR4, and their chemokine ligands were evaluated in liver metastases of colorectal cancer in order to study their correlation with overall and disease-free survival of patients having received, or not received, a neoadjuvant chemotherapy regimen. Quantitative RT-PCR and CXCR2 immunohistochemical staining were carried out using CRC liver ...[more]