Ontology highlight
ABSTRACT:
SUBMITTER: Geetha D
PROVIDER: S-EPMC4378104 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Geetha Duvuru D Specks Ulrich U Stone John H JH Merkel Peter A PA Seo Philip P Spiera Robert R Langford Carol A CA Hoffman Gary S GS Kallenberg Cees G M CG St Clair E William EW Fessler Barri J BJ Ding Linna L Tchao Nadia K NK Ikle David D Jepson Brett B Brunetta Paul P Fervenza Fernando C FC
Journal of the American Society of Nephrology : JASN 20141107 4
Rituximab (RTX) is non-inferior to cyclophosphamide (CYC) followed by azathioprine (AZA) for remission-induction in severe ANCA-associated vasculitis (AAV), but renal outcomes are unknown. This is a post hoc analysis of patients enrolled in the Rituximab for ANCA-Associated Vasculitis (RAVE) Trial who had renal involvement (biopsy proven pauci-immune GN, red blood cell casts in the urine, and/or a rise in serum creatinine concentration attributed to vasculitis). Remission-induction regimens were ...[more]