Pathogenicity of 2 porcine deltacoronavirus strains in gnotobiotic pigs.
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ABSTRACT: To verify whether porcine deltacoronavirus infection induces disease, we inoculated gnotobiotic pigs with 2 virus strains (OH-FD22 and OH-FD100) identified by 2 specific reverse transcription PCRs. At 21-120 h postinoculation, pigs exhibited severe diarrhea, vomiting, fecal shedding of virus, and severe atrophic enteritis. These findings confirm that these 2 strains are enteropathogenic in pigs.
SUBMITTER: Jung K
PROVIDER: S-EPMC4378491 | biostudies-literature |
REPOSITORIES: biostudies-literature
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