Ontology highlight
ABSTRACT:
SUBMITTER: Climer S
PROVIDER: S-EPMC4380243 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Climer Sharlee S Templeton Alan R AR Zhang Weixiong W
Nature communications 20150327
Gephyrin is a highly conserved gene that is vital for the organization of proteins at inhibitory receptors, molybdenum cofactor biosynthesis and other diverse functions. Its specific function is intricately regulated and its aberrant activities have been observed for a number of human diseases. Here we report a remarkable yin-yang haplotype pattern encompassing gephyrin. Yin-yang haplotypes arise when a stretch of DNA evolves to present two disparate forms that bear differing states for nucleoti ...[more]