Ontology highlight
ABSTRACT:
SUBMITTER: Kemena C
PROVIDER: S-EPMC4384290 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Kemena Carsten C Bitard-Feildel Tristan T Bornberg-Bauer Erich E
BMC bioinformatics 20150128
<h4>Background</h4>Proteins are composed of domains, protein segments that fold independently from the rest of the protein and have a specific function. During evolution the arrangement of domains can change: domains are gained, lost or their order is rearranged. To facilitate the analysis of these changes we propose the use of multiple domain alignments.<h4>Results</h4>We developed an alignment program, called MDAT, which aligns multiple domain arrangements. MDAT extends earlier programs which ...[more]