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The importance of loop length on the stability of i-motif structures.


ABSTRACT: Using UV and srCD spectroscopy it is found that loop length within the i-motif structure is important for both thermal and pH stability, but in contrast to previous statements, it is the shorter loops that exhibit the highest stability.

SUBMITTER: Gurung SP 

PROVIDER: S-EPMC4384421 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature

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The importance of loop length on the stability of i-motif structures.

Gurung Sarah P SP   Schwarz Christine C   Hall James P JP   Cardin Christine J CJ   Brazier John A JA  

Chemical communications (Cambridge, England) 20150401 26


Using UV and srCD spectroscopy it is found that loop length within the i-motif structure is important for both thermal and pH stability, but in contrast to previous statements, it is the shorter loops that exhibit the highest stability. ...[more]

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