Crystal structure of 2-[4-(4-chloro-phen-yl)-1-(4-meth-oxy-phen-yl)-2-oxoazetidin-3-yl]benzo[de]iso-quinoline-1,3-dione dimethyl sulfoxide monosolvate.

ABSTRACT: In the title solvated compound, C28H19N2O4·C2H6OS, the central ?-lactam ring is almost planar (r.m.s. deviation = 0.002?Å). It makes dihedral angles of 1.92?(11), 83.23?(12) and 74.90?(10)° with the meth-oxy- and chloro-phenyl rings and the ring plane of the 1H-benzo[de]iso-quinoline-1,3(2H)-dione group [maximum deviation = 0.089?(1)], respectively. An intra-molecular C-H?O hydrogen bond closes an S(6) ring and helps to establish the near coplanarity of the ?-lactam and meth-oxy-benzene rings. In the crystal, the components are linked by C-H?O hydrogen bonds, C-H?? inter-actions and aromatic ?-? stacking inter-actions [centroid-to-centroid distances = 3.6166?(10) and 3.7159?(10)?Å], resulting in a three-dimensional network, The dimethyl sulfoxide solvent mol-ecule is disordered over two sets of sites in a 0.847?(2):0.153?(2) ratio.

SUBMITTER: Celik I 

PROVIDER: S-EPMC4384601 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature