Ontology highlight
ABSTRACT:
SUBMITTER: Yang DR
PROVIDER: S-EPMC4385526 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
World journal of gastroenterology 20150401 13
Hepatitis C virus (HCV) is a major human pathogen of chronic hepatitis and related liver diseases. Innate immunity is the first line of defense against invading foreign pathogens, and its activation is dependent on the recognition of these pathogens by several key sensors. The interferon (IFN) system plays an essential role in the restriction of HCV infection via the induction of hundreds of IFN-stimulated genes (ISGs) that inhibit viral replication and spread. However, numerous factors that tri ...[more]