Ontology highlight
ABSTRACT:
SUBMITTER: Fessel WJ
PROVIDER: S-EPMC4388049 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Fessel W Jeffrey WJ Anderson Brooke B Follansbee Stephen E SE Winters Mark A MA Lewis Stanley T ST Weinheimer Steven P SP Petropoulos Christos J CJ Shafer Robert W RW
Antiviral research 20111004 3
The availability of 24 antiretroviral (ARV) drugs within six distinct drug classes has transformed HIV-1 infection (AIDS) into a treatable chronic disease. However, the ability of HIV-1 to develop resistance to multiple classes continues to present challenges to the treatment of many ARV treatment-experienced patients. In this case report, we describe the response to ibalizumab, an investigational CD4-binding monoclonal antibody (mAb), in a patient with advanced immunodeficiency and high-level f ...[more]