Ontology highlight
ABSTRACT:
SUBMITTER: Ding R
PROVIDER: S-EPMC4388185 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Acta crystallographica. Section F, Structural biology communications 20150321 Pt 4
The 2-carboxy-6-hydroxyoctahydroindole moiety is an essential residue for the antithrombotic activity of aeruginosins, which are a class of cyanobacteria-derived bioactive linear tetrapeptides. The biosynthetic pathway of the 2-carboxy-6-hydroxyoctahydroindole moiety has not yet been resolved. AerF was indicated to be involved in the biosynthesis of the 2-carboxy-6-hydroxyoctahydroindole moiety. This study reports the cloning, expression, purification, crystallization and preliminary X-ray diffr ...[more]