Ontology highlight
ABSTRACT:
SUBMITTER: Mani J
PROVIDER: S-EPMC4389251 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Mani Jan J Desy Silvia S Niemann Moritz M Chanfon Astrid A Oeljeklaus Silke S Pusnik Mascha M Schmidt Oliver O Gerbeth Carolin C Meisinger Chris C Warscheid Bettina B Schneider André A
Nature communications 20150326
Mitochondrial protein import is essential for all eukaryotes and mediated by hetero-oligomeric protein translocases thought to be conserved within all eukaryotes. We have identified and analysed the function and architecture of the non-conventional outer membrane (OM) protein translocase in the early diverging eukaryote Trypanosoma brucei. It consists of six subunits that show no obvious homology to translocase components of other species. Two subunits are import receptors that have a unique top ...[more]