Ontology highlight
ABSTRACT:
SUBMITTER: Rey M
PROVIDER: S-EPMC4391204 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Rey Martial M Sarpe Vladimir V Burns Kyle M KM Buse Joshua J Baker Charles A H CA van Dijk Marc M Wordeman Linda L Bonvin Alexandre M J J AM Schriemer David C DC
Structure (London, England : 1993) 20140918 10
The integration of biophysical data from multiple sources is critical for developing accurate structural models of large multiprotein systems and their regulators. Mass spectrometry (MS) can be used to measure the insertion location for a wide range of topographically sensitive chemical probes, and such insertion data provide a rich, but disparate set of modeling restraints. We have developed a software platform that integrates the analysis of label-based MS and tandem MS (MS(2)) data with prote ...[more]