Signaling by exosomal microRNAs in cancer.
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ABSTRACT:
SUBMITTER: Falcone G
PROVIDER: S-EPMC4391656 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Publications
Signaling by exosomal microRNAs in cancer.
Falcone Germana G Felsani Armando A D'Agnano Igea I
Journal of experimental & clinical cancer research : CR 20150402
A class of small non-coding RNAs, the microRNAs (miRNAs), have recently attracted great attention in cancer research since they play a central role in regulation of gene-expression and miRNA aberrant expression is found in almost all types of human cancer. The discovery of circulating miRNAs in body fluids and the finding that they are often tumor specific and can be detected early in tumorigenesis has soon led to the evaluation of their possible use as cancer biomarkers and treatment-response p ...[more]
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