Ontology highlight
ABSTRACT:
SUBMITTER: Rivera LB
PROVIDER: S-EPMC4393787 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Rivera Lee B LB Bergers Gabriele G
Trends in immunology 20150311 4
Angiogenesis is a hallmark of cancer because its induction is indispensable to fuel an expanding tumor. The tumor microenvironment contributes to tumor vessel growth, and distinct myeloid cells recruited by the tumor have been shown not only to support angiogenesis but also to foster an immune suppressive environment that supports tumor expansion and progression. Recent findings suggest that the intertwined regulation of angiogenesis and immune modulation can offer therapeutic opportunities for ...[more]