Ontology highlight
ABSTRACT:
SUBMITTER: Sarou-Kanian V
PROVIDER: S-EPMC4402646 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Sarou-Kanian Vincent V Joudiou Nicolas N Louat Fanny F Yon Maxime M Szeremeta Frédéric F Même Sandra S Massiot Dominique D Decoville Martine M Fayon Franck F Beloeil Jean-Claude JC
Scientific reports 20150420
We have developed new methods enabling in vivo localization and identification of metabolites through their (1)H NMR signatures, in a drosophila. Metabolic profiles in localized regions were obtained using HR-MAS Slice Localized Spectroscopy and Chemical Shift Imaging at high magnetic fields. These methods enabled measurement of metabolite contents in anatomic regions of the fly, demonstrated by a decrease in β-alanine signals in the thorax of flies showing muscle degeneration. ...[more]