Ontology highlight
ABSTRACT:
SUBMITTER: Weiner A
PROVIDER: S-EPMC4405355 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Weiner Assaf A Hsieh Tsung-Han S TH Appleboim Alon A Chen Hsiuyi V HV Rahat Ayelet A Amit Ido I Rando Oliver J OJ Friedman Nir N
Molecular cell 20150319 2
Covalent histone modifications are highly conserved and play multiple roles in eukaryotic transcription regulation. Here, we mapped 26 histone modifications genome-wide in exponentially growing yeast and during a dramatic transcriptional reprogramming-the response to diamide stress. We extend prior studies showing that steady-state histone modification patterns reflect genomic processes, especially transcription, and display limited combinatorial complexity. Interestingly, during the stress resp ...[more]