Voltage controlled nano-injection system for single-cell surgery.
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ABSTRACT:
SUBMITTER: Adam Seger R
PROVIDER: S-EPMC4406976 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Publications
Voltage controlled nano-injection system for single-cell surgery.
Adam Seger R R Actis Paolo P Penfold Catherine C Maalouf Michelle M Vilozny Boaz B Pourmand Nader N
Nanoscale 20120816 19
Manipulation and analysis of single cells is the next frontier in understanding processes that control the function and fate of cells. Herein we describe a single-cell injection platform based on nanopipettes. The system uses scanning microscopy techniques to detect cell surfaces, and voltage pulses to deliver molecules into individual cells. As a proof of concept, we injected adherent mammalian cells with fluorescent dyes. ...[more]
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