Ontology highlight
ABSTRACT:
SUBMITTER: Mainland JD
PROVIDER: S-EPMC4412152 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Mainland Joel D JD Li Yun R YR Zhou Ting T Liu Wen Ling L WL Matsunami Hiroaki H
Scientific data 20150203
Although the human olfactory system is capable of discriminating a vast number of odors, we do not currently understand what chemical features are encoded by olfactory receptors. In large part this is due to a paucity of data in a search space covering the interactions of hundreds of receptors with billions of odorous molecules. Of the approximately 400 intact human odorant receptors, only 10% have a published ligand. Here we used a heterologous luciferase assay to screen 73 odorants against a c ...[more]