Nanofibrous hydrogels with spatially patterned biochemical signals to control cell behavior.
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ABSTRACT:
SUBMITTER: Wade RJ
PROVIDER: S-EPMC4412590 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Publications
Nanofibrous hydrogels with spatially patterned biochemical signals to control cell behavior.
Wade Ryan J RJ Bassin Ethan J EJ Gramlich William M WM Burdick Jason A JA
Advanced materials (Deerfield Beach, Fla.) 20150112 8
The ability to spatially pattern biochemical signals into nanofibrous materials using thiol-ene reactions of thiolated molecules to presented norbornene groups is demonstrated. This approach is used to pattern three molecules independently within one scaffold, to pattern molecules through the depth of a scaffold, and to spatially control cell adhesion and morphology. ...[more]
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