Ontology highlight
ABSTRACT:
SUBMITTER: Ortega FJ
PROVIDER: S-EPMC4413548 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Ortega Francisco José FJ Moreno María M Mercader Josep María JM Moreno-Navarrete José María JM Fuentes-Batllevell Núria N Sabater Mònica M Ricart Wifredo W Fernández-Real José Manuel JM
Clinical epigenetics 20150424
<h4>Background</h4>The relevance of microRNAs (miRNAs) in adipose tissue is increasingly recognized, being intrinsically linked to different pathways, including obesity-related inflammation. In this study, we aimed to characterize the changes induced by inflammation on the miRNA pattern of human adipocytes and macrophages. Therefore, an extensive profile of 754 common miRNAs was assessed in cells (human primary mature adipocytes, and the macrophage-like cell line THP-1) and in their supernatants ...[more]