Ontology highlight
ABSTRACT:
SUBMITTER: Recuenco MC
PROVIDER: S-EPMC4413762 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Recuenco Mariam C MC Ohmori Tomoko T Tanigawa Shunsuke S Taguchi Atsuhiro A Fujimura Sayoko S Conti Mary Anne MA Wei Qize Q Kiyonari Hiroshi H Abe Takaya T Adelstein Robert S RS Nishinakamura Ryuichi R
Journal of the American Society of Nephrology : JASN 20140828 5
The kidney develops from reciprocal interactions between the metanephric mesenchyme and ureteric bud. The mesenchyme transforms into epithelia and forms complicated nephron structures, whereas the ureteric bud extends its pre-existing epithelial ducts. Although the roles are well established for extracellular stimuli, such as Wnt and Notch, it is unclear how the intracellular cytoskeleton regulates these morphogenetic processes. Myh9 and Myh10 encode nonmuscle myosin II heavy chains, and Myh9 mu ...[more]