Ontology highlight
ABSTRACT:
SUBMITTER: Hausburg MA
PROVIDER: S-EPMC4415119 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Hausburg Melissa A MA Doles Jason D JD Clement Sandra L SL Cadwallader Adam B AB Hall Monica N MN Blackshear Perry J PJ Lykke-Andersen Jens J Olwin Bradley B BB
eLife 20150327
Skeletal muscle satellite cells in their niche are quiescent and upon muscle injury, exit quiescence, proliferate to repair muscle tissue, and self-renew to replenish the satellite cell population. To understand the mechanisms involved in maintaining satellite cell quiescence, we identified gene transcripts that were differentially expressed during satellite cell activation following muscle injury. Transcripts encoding RNA binding proteins were among the most significantly changed and included t ...[more]