Ontology highlight
ABSTRACT:
SUBMITTER: Aftab DT
PROVIDER: S-EPMC4422050 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20111001 10
Recent advances in the treatment of prostate cancer have resulted in improved outcomes, including longer survival, but new options are needed for treating patients with castration-resistant disease, particularly in the presence of bone metastasis. Data from preclinical models and clinical biomarker studies indicate that antiangiogenic agents should be a promising treatment for this patient population, and multiple agents in this class have demonstrated activity in early-stage clinical trials. Pi ...[more]