Ontology highlight
ABSTRACT:
SUBMITTER: O'Brien KM
PROVIDER: S-EPMC4423525 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
O'Brien Katie M KM Fei Chunyuan C Sandler Dale P DP Nichols Hazel B HB DeRoo Lisa A LA Weinberg Clarice R CR
American journal of epidemiology 20150218 10
Estrogen plus progestin hormone therapy (HT) is associated with an increased risk of postmenopausal breast cancer, but few studies have examined the impact of HT use on the risk of breast cancer in younger women. We assessed the association between estrogen plus progestin HT or unopposed estrogen HT and young-onset breast cancer using data from the Two Sister Study (2008-2010), a sister-matched study of 1,419 cases diagnosed with breast cancer before the age of 50 years and 1,665 controls. We as ...[more]