Ontology highlight
ABSTRACT:
SUBMITTER: Jarosz DF
PROVIDER: S-EPMC4424049 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Jarosz Daniel F DF Lancaster Alex K AK Brown Jessica C S JCS Lindquist Susan S
Cell 20140801 5
[GAR(+)] is a protein-based element of inheritance that allows yeast (Saccharomyces cerevisiae) to circumvent a hallmark of their biology: extreme metabolic specialization for glucose fermentation. When glucose is present, yeast will not use other carbon sources. [GAR(+)] allows cells to circumvent this "glucose repression." [GAR(+)] is induced in yeast by a factor secreted by bacteria inhabiting their environment. We report that de novo rates of [GAR(+)] appearance correlate with the yeast's ec ...[more]