Ontology highlight
ABSTRACT:
SUBMITTER: Jarosz DF
PROVIDER: S-EPMC4424051 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Cell 20140801 5
In experimental science, organisms are usually studied in isolation, but in the wild, they compete and cooperate in complex communities. We report a system for cross-kingdom communication by which bacteria heritably transform yeast metabolism. An ancient biological circuit blocks yeast from using other carbon sources in the presence of glucose. [GAR(+)], a protein-based epigenetic element, allows yeast to circumvent this "glucose repression" and use multiple carbon sources in the presence of glu ...[more]