Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez-Gil DJ
PROVIDER: S-EPMC4426395 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Rodriguez-Gil Diego J DJ Bartel Dianna L DL Jaspers Austin W AW Mobley Arie S AS Imamura Fumiaki F Greer Charles A CA
Proceedings of the National Academy of Sciences of the United States of America 20150420 18
Odorant receptors (OR) are strongly implicated in coalescence of olfactory sensory neuron (OSN) axons and the formation of olfactory bulb (OB) glomeruli. However, when ORs are first expressed relative to basal cell division and OSN axon extension is unknown. We developed an in vivo fate-mapping strategy that enabled us to follow OSN maturation and axon extension beginning at basal cell division. In parallel, we mapped the molecular development of OSNs beginning at basal cell division, including ...[more]