Ontology highlight
ABSTRACT:
SUBMITTER: Otvos R
PROVIDER: S-EPMC4426949 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Ötvös Rita R Szulkin Adam A Hillerdal Carl-Olof CO Celep Aytekin A Yousef-Fadhel Eviane E Skribek Henriette H Hjerpe Anders A Székely László L Dobra Katalin K
Genes & cancer 20150301 3-4
We propose to assess the therapeutic value of biomarker-guided individualized chemotherapy in patients with metastasizing lung adenocarcinoma. In this study, we used primary cells from pleural effusions from sixteen patients diagnosed with adenocarcinomas originating in the lung and from four patients with no malignant diagnosis. The ex vivo drug sensitivity of primary cells was assessed for 32 chemotherapeutical drugs. Linear regression analyses were performed to examine possible correlations b ...[more]