Ontology highlight
ABSTRACT:
SUBMITTER: Lorimer DD
PROVIDER: S-EPMC4427167 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Acta crystallographica. Section F, Structural biology communications 20150421 Pt 5
Three structures of the histidine triad family protein from Entamoeba histolytica, the causative agent of amoebic dysentery, were solved at high resolution within the Seattle Structural Genomics Center for Infectious Disease (SSGCID). The structures have sulfate (PDB entry 3oj7), AMP (PDB entry 3omf) or GMP (PDB entry 3oxk) bound in the active site, with sulfate occupying the same space as the α-phosphate of the two nucleotides. The C(α) backbones of the three structures are nearly superimposabl ...[more]