Ontology highlight
ABSTRACT:
SUBMITTER: Haynes CL
PROVIDER: S-EPMC4427168 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Haynes Carole L F CL Ameloot Paul P Remaut Han H Callewaert Nico N Sterckx Yann G J YG Magez Stefan S
Acta crystallographica. Section F, Structural biology communications 20150421 Pt 5
Sialidases and trans-sialidases play important roles in the life cycles of various microorganisms. These enzymes can serve nutritional purposes, act as virulence factors or mediate cellular interactions (cell evasion and invasion). In the case of the protozoan parasite Trypanosoma vivax, trans-sialidase activity has been suggested to be involved in infection-associated anaemia, which is the major pathology in the disease nagana. The physiological role of trypanosomal trans-sialidases in host-par ...[more]