Peptide aptamers: development and applications.
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ABSTRACT:
SUBMITTER: Reverdatto S
PROVIDER: S-EPMC4428161 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Peptide aptamers: development and applications.
Reverdatto Sergey S Burz David S DS Shekhtman Alexander A
Current topics in medicinal chemistry 20150101 12
Peptide aptamers are small combinatorial proteins that are selected to bind to specific sites on their target molecules. Peptide aptamers consist of short, 5-20 amino acid residues long sequences, typically embedded as a loop within a stable protein scaffold. Various peptide aptamer scaffolds and in vitro and in vivo selection techniques are reviewed with emphasis on specific biomedical, bioimaging, and bioanalytical applications. ...[more]
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