Ontology highlight
ABSTRACT:
SUBMITTER: Haney MJ
PROVIDER: S-EPMC4430381 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Haney Matthew J MJ Klyachko Natalia L NL Zhao Yuling Y Gupta Richa R Plotnikova Evgeniya G EG He Zhijian Z Patel Tejash T Piroyan Aleksandr A Sokolsky Marina M Kabanov Alexander V AV Batrakova Elena V EV
Journal of controlled release : official journal of the Controlled Release Society 20150331
Exosomes are naturally occurring nanosized vesicles that have attracted considerable attention as drug delivery vehicles in the past few years. Exosomes are comprised of natural lipid bilayers with the abundance of adhesive proteins that readily interact with cellular membranes. We posit that exosomes secreted by monocytes and macrophages can provide an unprecedented opportunity to avoid entrapment in mononuclear phagocytes (as a part of the host immune system), and at the same time enhance deli ...[more]