Ontology highlight
ABSTRACT:
SUBMITTER: Yang X
PROVIDER: S-EPMC4433588 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Yang Xiao X van der Donk Wilfred A WA
ACS chemical biology 20150310 5
Lanthipeptides are members of the ribosomally synthesized and post-translationally modified peptides (RiPPs). They are generated in two biosynthetic steps: dehydration of Ser and Thr residues to the corresponding dehydroamino acids and subsequent conjugate addition by the thiol of Cys residues to generate the characteristic lanthionine and methyllanthionine thioether-bridged structures. Typically, a lanthipeptide contains multiple thioether cross-links. Recent studies have proposed that the fina ...[more]