Association of 42 SNPs with genetic risk for cervical cancer: an extensive meta-analysis.

ABSTRACT:

Background

A large number of single nucleotide polymorphisms (SNPs) associated with cervical cancer have been identified through candidate gene association studies and genome-wide association studies (GWAs). However, some studies have yielded different results for the same SNP. To obtain a more comprehensive understanding, we performed a meta-analysis on previously published case-control studies involving the SNPs associated with cervical cancer.

Methods

Electronic searches of PubMed and Embase were conducted for all publications about the association between gene polymorphisms and cervical cancer. One-hundred and sixty-seven association studies were included in our research. For each SNP, three models (the allele, dominant and recessive effect models) were adopted in the me

SUBMITTER: Wang S 

PROVIDER: S-EPMC4436168 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature